نتایج جستجو برای: drug resistance associated protein 1
تعداد نتایج: 5141910 فیلتر نتایج به سال:
purpose: the aim of the present study was to detect the expression of p-glycoprotein (p-gp) and multi-drug resistance associated protein 1 (mrp1) in retinoblastoma tumors, and analyze the relationship between its expression, the clinico-pathological features and recurrence. methods: p-gp and mrp1 expression in formalin-fixed paraffin-embedded retinoblastoma bearing ocular tissue sections from 2...
Objective: Addiction to narcotic drugs is associated with cardiovascular diseases; and increased levels of biomarkers, such as C-reactive protein and fibrinogen are independently correlated with the risk of cardiovascular diseases. Therefore, this study aimed to investigate the effects of 8 weeks of resistance training on C-reactive protein and fibrinogen levels in drug addicted men. Method: In...
conclusions the study revealed a high prevalence of multi-drug resistance (mdr), class 1 integron, sccmec type iii, and spa type t030 amongst mrsa associated with burn wounds in an iranian hospital. the existence of sccmec type iii in burn patients emphasizes the nosocomial origin of these strains. objectives the aim of this study was to determine the distribution and molecular types of mrsa in...
Some varieties of human cancers become resistant, or, are intrinsically resistant to treatment with conventional drug therapies. This phenomenon is due largely to over-expression of the ATP binding cassette, (ABC), super-family of membrane transporters. In this regard, 170 kDa plasma membrane ATP-dependent pump, known as P-glycoprotein are the most important. Other members of multi-drug resista...
background: the h9n2 subtype of influenza a viruses is considered to be widespread in poultry industry. adamantane is a group of antiviral agents which is effective both in prevention and treatment of influenza a virus infections. these drugs inhibit m2 protein ion channel which has role on viral replication. objectives: the main objective of this study is to evaluate m gene of avian influenza ...
Intrinsic and/or acquired resistance to chemotherapy is the major obstacle to overcome in the treatment of patients with ovarian carcinoma. The aim of the present study was to investigate the prognostic value of drug resistance-associated proteins P-glycoprotein (P-gp), multidrug resistance-associated protein 1 (MRP1), canalicular multispecific organic anion transporter (c-MOAT/MRP2), and lung ...
Multidrug resistance (MDR) is a complex phenomenon in which many different genes regulating drug transport, cellular repair, detoxification and drug metabolism are involved. Nevertheless, in most drug resistant cell lines and cancer patients up-regulation of ABC-transporter genes such as MDR associated Protein (MRP1) gene could be at the basis of the drug resistance phenotype. We aimed to decre...
multidrug resistance (mdr) is a complex phenomenon in which many different genes regulating drug transport, cellular repair, detoxification and drug metabolism are involved. nevertheless, in most drug resistant cell lines and cancer patients up-regulation of abc-transporter genes such as mdr associated protein (mrp1) gene could be at the basis of the drug resistance phenotype. we aimed to decre...
conclusions the present study reports on a high rate of multi-drug resistance, the predominance of the frequency of class 1 integron, and the emergence of spa type t790 among iranian staphylococcus aureus strains. the results revealed that the dissemination of multi-drug resistance among staphylococcus aureus isolates may be associated with the presence of integrons. therefore, continuous surve...
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